
Transcription Factors and Human Genetic Disease (English, Gregg Semenza)
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About the Book
Several general principles have emerged from the study of human transcription factors. First, germline mutations in genes encoding transcription factors result in malformation syndromes in which the development of multiple body structures is affected. Second, somatic mutations involving many of the same genes contribute to tumorigenesis. Third, transcriptional regulatory mechanisms demonstrate remarkable evolutionary conservation. Fourth, prenata…
ISBN: 9780195112399
Book Specifications
| ISBN-13 | 9780195112399 |
| ISBN-10 | 0195112393 |
| Publisher | Oxford University Press |
| Category | Oxford University Press |
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