Mathematical Modeling and Simulation in Enteric Neurobiology

The lack of scientists equally trained and prepared to understand both mathematics and biology/medicine hampers the development and application of computer simulation methods in biology and neurogastrobiology. Currently, there are no texts for navigating the extensive and intricate field of mathematical and computational modeling in neurogastrobiology. This book bridges the gap between mathematicians, computer scientists and biologists, and thus assists in the study and analysis of complex biological phenomena that cannot be done through traditional in vivo and in vitro experimental approaches.The book recognizes the complexity of biological phenomena under investigation and treats the subject matter with a degree of mathematical rigor. Special attention is given to computer simulations for interpolation and extrapolation of electromechanical and chemoelectrical phenomena, nonlinear self-sustained electromechanical wave activity, pharmacological effects including co-localization and co-transmission by multiple neurotransmitters, receptor polymodality, and drug interactions.